110-85-0 Piperazine

CAS Number:  110-85-0

OtherNames:PIPERAZINE;1,4-DIAZACYCLOHEXANE;AKOS 90646;AKOS BBS-00004315;HEXAHYDRO-1,4-DIAZINE;HEXAHYDROPYRAZINE;DIETHYLENEDIAMINE;Anhydrous Piperazine (PIP)

Formula:C4H10N2


Details

PRODUCT INTRODUCTION

Piperazine is an important pharmaceutical intermediate, which is mainly used in the production of intestinal worm repellent drugs such as piperazine phosphate, piperazine citrate, Fluphenazine, Qiangtongding, Rifampicin, trimethoprim and other chemobooks. It is also used in the production of surfactants such as wetting agents, emulsifiers, dispersants, as well as plastic processing aids such as antioxidants, preservatives, stabilizers, and rubber additives.

PHYSICAL AND CHEMICAL PROPERTIES

Appearance: Yellow or orange red transparent viscous liquid
 

 

Structure

Melting Point 109-112 °C (lit.)
Boiling Point 145-146 °C (lit.)
Storage Conditions Store below +30°C.
Solubility H2O: 0.1 M at 20 °C, clear, colorless
Color White to slightly yellow
Form Crystalline Flakes
Stability Stable. Hygroscopic. Light sensitive. Flammable. Incompatible with strong oxidizing agents.
Odor at 0.10 % in dipropylene glycol. ammoniacal
Soluble 150 g/L (20 ºC)
Density 1,1 g/cm3

APPLICATIONS

purpose

Piperazine, also known as expelling roundworms, is a safe and effective anti roundworm and anti pinworm drug. China's "Veterinary Pharmacopoeia" includes piperazine citrate and piperazine phosphate. This product can paralyze roundworm muscles, prevent the worm body from attaching to the host intestinal wall, and then be excreted from the body with feces.

application

Piperazine is clinically used for intestinal Ascariasis, effective for incomplete Bowel obstruction caused by ascaris lumbricoides or early biliary Ascariasis, and also for Pinworm infection infection. Various salts of piperazine (chemically stable than piperazine) are low toxicity and effective anti roundworm drugs. In addition to roundworms, they also have certain effects on esophagostomy nematodes and pointed tail nematodes, and have been widely used in veterinary clinical practice. The repellent effect of piperazine is an anticholinergic effect on the neuromuscular junction of roundworms, thereby blocking the transmission of nerve impulses; At the same time, the function of producing succinic acid on the worm body is also blocked, resulting in paralysis of the worm body, loss of its ability to attach to the host intestinal wall, and excretion from the body through intestinal peristalsis.

PACKING OPTIONS

Drums

IBC

Tank

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